Team VPE

  1. Home
  2. Research Teams
  3. Artificial Intelligence
  4. Team VPE

Artificial Intelligence

Team VPE

Next Generation Virtual Patient Engine for Clinical Translation of Drug Candidates


The goal of team VPE is to develop a versatile computational platform that can predict the efficacy of first- or best-in-class drug candidates in virtual patient populations at an unprecedented accuracy, thereby addressing one of the most critical bottlenecks of the pharmaceutical industry today: a 90% failure rate of new drug candidates during clinical development. In partnership with Sanofi, the VPE team will develop innovative artificial intelligence methods to build the virtual patient platform. As a proof-of-concept, the initial platform will focus on chronic immune-mediated diseases such as atopic dermatitis (AD) and inflammatory bowel disease (IBD), where new medication that can address patient heterogeneity is needed.

 Mentors
  • Dr. Tommaso Andreani (Industry Mentor)
    Sr. Principal Data Scientist – Disease Modeling Innovation Lead, Sanofi
  • Dr. Jan Korbel (Academic Mentor)
    Head of Data Science, European Molecular Biology Laboratory
 Publications
  1. Gurdeep Singh, Lilija Wehling, Ahmad Wisnu Mulyadi, Rakesh Hadne Sreenath, Douglas McCloskey (BioMed X Institute), Thomas Klabunde, Tommaso Andreani (Sanofi) (2025)
    TALK2BIOMODELS AND TALK2KNOWLEDGEGRAPHS: AI AGENT-BASED APPLICATION FOR PREDICTION OF PATIENT BIOMARKERS AND REASONING OVER BIOMEDICAL KNOWLEDGE GRAPHS
     MLGenX 2025, ICLR Conference Workshop Paper

You can also find us on GitHub

Team Location BioMed X Institute Heidelberg

The research of this team is kindly supported by Sanofi.

Our Team Members

Dr. Gurdeep Singh

Group Leader

 Short Bio
  • 2021 – 2023: PostDoc, Russell lab, Heidelberg University, Germany
  • 2017 – 2021: PhD, Russell lab, Heidelberg University, Germany
  • 2015 – 2017: Research Assistant, Heidelberg University, Germany
  • 2014 – 2015: Bachelor’s thesis at Vrije Universiteit Brussel, Belgium &Heidelberg University, Germany
  • 2010 – 2015: Bachelor of Engineering (Electrical and Electronics), BITS Pilani, India
 Contact

Dr. Lilija Wehling

Computational Biologist

 Short Bio
  • 2021 – 2022: Postdoctoral researcher at the Molecular Hepatopathology Laboratory, Heidelberg University Hospital
  • 2017 – 2021: PhD Student in Systems Biology at BioQuant (Heidelberg University) and the Pathology Institute of the Heidelberg University Hospital
  • 2013 – 2016: Master of Science in Systems Biology, Heidelberg University
 Contact

Dr. Ahmad Wisnu Mulyadi

Algorithm Researcher

 Short Bio
  • 2018 – 2024: PhD in the Dept. of Brain & Cognitive Engineering, Korea University, South Korea
  • 2015 – 2016: Master of Engineering in the Dept. of Interdisciplinary Program of Information Systems, Pukyong National University, South Korea
  • 2013 – 2016: Master of Science in the Dept. of Electrical Engineering, Institut Teknologi Bandung, Indonesia
 Contact

Sanjana Balaji Kuttae

Computational Biologist, Research Assistant

 Short Bio
  • 2018 – 2023: Master of Science in Bioinformatics, Universität des Saarlandes, Saarbrücken, Germany
  • 2011 – 2015: Bachelor of Technology in Bioinformatics, SRM University, Chennai, India
 Contact

Rakesh Hadne Sreenath

Intern

 Short Bio
  • 2023 – Present: Master of Science in Applied Data Science and Analytics, SRH University, Germany
  • 2022 – 2023: Post-Degree Diploma in Data Science, Purdue University, USA
  • 2021 – 2023: Software Engineer, Tech Mahindra, India
  • 2016 – 2020: Bachelor of Engineering in Electronics and Communication Engineering, UBDT Collage of Engineering, India
 Contact

Ansh Kumar

Master's Student

 Short Bio
  • April 2024 – present: Master of Science in Applied Data Science and Analytics, SRH University, Heidelberg, Germany
  • January 2023 – February 2023: NLP & Automation Intern, R. Chandra & Associates, Lucknow, India
  • November 2022 – November 2022: Data Analyst Intern, Honeywell, Roorkee, India
  • July 2022 – September 2022: Database Intern, CSIR – Indian Institute of Petroleum (IIP), Dehradun, India
  • 2019 – 2023: Bachelor of Technology in Computer Science and Engineering, Quantum University, Roorkee, India
 Contact

Learn more about BioMed X

Team BDB

Team BDB

The objective of the research group is to develop an in vivo continuous monitoring biosensor for direct detection of small molecule biomarkers in brain tissue of rodent models for elucidating pharmacodynamic (PD) effect and pharmacokinetic (PK) parameters of drugs against neuropsychiatric diseases.

Read more

Team TMI

Team TMI

The project’s cores are to develop a ligand specific for a target cell and establish quantitative assessment methods to monitor macromolecular drug delivery across the intestinal epithelial barrier.

Read more